• Users Online: 276
  • Home
  • Print this page
  • Email this page
Home About us Editorial board Search Ahead of print Current issue Archives Submit article Instructions Subscribe Contacts Login 
REVIEW ARTICLE
Year : 2022  |  Volume : 9  |  Issue : 3  |  Page : 211-216

Influence of Helicobacter pylori infection on periodontitis: A meta-analysis


Department of Stomatology, Oral Medicine Unit, Faculty of Dentistry, University of Granada, Granada, Spain

Correspondence Address:
Alberto Rodriguez-Archilla
Department of Stomatology, Oral Medicine Unit, Faculty of Dentistry, University of Granada, Colegio Maximo, s/n. Campus de Cartuja, 18071.Granada
Spain
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jdrr.jdrr_103_22

Rights and Permissions

Background: Helicobacter pylori detection in dental plaque, saliva, or oral mucosa would allow to include this bacteria as a member of the normal oral microbiota and have an etiological role in periodontitis. Objective: The objective of this study is to assess the possible relationship of H. pylori with periodontitis. Methods: A search for studies on H. pylori and periodontitis was conducted in the following databases: PubMed (MEDLINE, Cochrane Library), Web of Science, and Scopus. The pooled prevalence was calculated according to DerSimonian and Laird method. For dichotomous outcomes, the estimates of effects of the intervention were expressed as odds ratios using Mantel–Haenszel method, and for continuous outcomes, the estimates of effects of the intervention were expressed as mean differences using the inverse-variance method, all with 95% confidence intervals. Results: Twenty-six studies with 4072 participants were included in this meta-analysis. Among periodontitis patients, the estimated prevalence of H. pylori detection was 47.93%. Periodontitis patients had 1.89 times more likely to be infected with H. pylori (P < 0.001) and also, an increase of 2.78 times the probability of H. pylori detection on dental plaque (P < 0.001). Similarly, H. pylori was 2.32 times more likely in the oral microbiota than in the gastric one (P < 0.001). Some periodontal parameters (plaque index, probing depth, and clinical attachment level) were significantly worse in positive H. pylori patients. Conclusions: H. pylori infection seems to aggravate periodontitis.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed458    
    Printed16    
    Emailed0    
    PDF Downloaded52    
    Comments [Add]    

Recommend this journal